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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD2
All Species:
6.06
Human Site:
S1068
Identified Species:
22.22
UniProt:
Q9BYW2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYW2
NP_054878.5
2564
287550
S1068
I
P
R
N
R
L
Q
S
V
V
V
V
P
K
N
Chimpanzee
Pan troglodytes
XP_516423
2549
285788
S1061
V
V
V
V
P
K
N
S
T
L
P
M
E
E
T
Rhesus Macaque
Macaca mulatta
XP_001113652
2550
286209
S1054
I
P
R
N
R
L
Q
S
V
V
V
V
P
K
N
Dog
Lupus familis
XP_864158
2562
287091
V1065
R
N
R
L
Q
S
V
V
V
V
P
K
N
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418510
2354
262767
C928
G
L
Q
A
E
S
R
C
S
P
R
G
M
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783359
3042
342758
E1127
D
K
I
A
D
N
D
E
E
T
I
C
D
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2LAE1
1759
193210
K333
D
L
S
V
M
N
E
K
M
L
K
N
H
V
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
92
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.7
Protein Similarity:
100
98.9
98
94.6
N.A.
N.A.
N.A.
N.A.
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.6
P-Site Identity:
100
6.6
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
29
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
0
% C
% Asp:
29
0
0
0
15
0
15
0
0
0
0
0
15
0
0
% D
% Glu:
0
0
0
0
15
0
15
15
15
0
0
0
15
29
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
0
0
0
15
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
29
0
15
0
0
0
0
0
0
0
15
0
0
0
0
% I
% Lys:
0
15
0
0
0
15
0
15
0
0
15
15
0
29
15
% K
% Leu:
0
29
0
15
0
29
0
0
0
29
0
0
0
0
0
% L
% Met:
0
0
0
0
15
0
0
0
15
0
0
15
15
0
0
% M
% Asn:
0
15
0
29
0
29
15
0
0
0
0
15
15
0
29
% N
% Pro:
0
29
0
0
15
0
0
0
0
15
29
0
29
0
0
% P
% Gln:
0
0
15
0
15
0
29
0
0
0
0
0
0
15
0
% Q
% Arg:
15
0
43
0
29
0
15
0
0
0
15
0
0
0
0
% R
% Ser:
0
0
15
0
0
29
0
43
15
0
0
0
0
15
0
% S
% Thr:
0
0
0
0
0
0
0
0
15
15
0
0
0
0
43
% T
% Val:
15
15
15
29
0
0
15
15
43
43
29
29
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _